Regulated Nodal signaling promotes differentiation of the definitive endoderm and mesoderm from ES cells
نویسندگان
چکیده
منابع مشابه
Regulated Nodal signaling promotes differentiation of the definitive endoderm and mesoderm from ES cells.
Nodal signaling induces the formation of the endoderm and mesoderm during gastrulation. Nodal expression persists until the definitive endoderm progenitor has completely formed, and disappears thereafter. A tightly regulated Nodal expression system is essential for the differentiation of embryonic stem (ES) cells into distinct tissue lineages. On this basis, we established an ES cell differenti...
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ژورنال
عنوان ژورنال: Journal of Cell Science
سال: 2007
ISSN: 1477-9137,0021-9533
DOI: 10.1242/jcs.004127